The brain’s plumbing needs a good cleaning and that might help fix Alzheimer’s disease and mental decline says Sandro Da Mesquita, who’s a postdoctoral researcher in the Department of Neuroscience at the University of Virginia School of Medicine . He is a first author on the new paper that describes their discovery in the journal Nature. He joins Les Sinclair to explain.  More: https://www.nature.com/articles/s41586-018-0368-8